ALFTP

the server URL, as well as the directory where the website you want to upload to is hosted. If you have more than one site, the application lets you organize them in categories, and even perform simultaneous downloads. ALFTP lets you restart failed downloads, customize the welcome message, allows anonymous access, and also supports files up to 2 gigabytes, among many other features. Aside from all that, the application has an elegant and intuitive design that's actually pretty easy on the eyes. Not to mention, ALFTP is also entirely free.